How does NMR provide the data & how does it become a metabolic profile?


At lifespin, the digitization of biological material takes place in two steps: 

In the first step, the sample is measured using a high-resolution NMR spectrometer. This takes less (!) than a minute. In this short time, the signals of all (!) molecules in the sample are recorded and this over a range of six orders of magnitude. This means that the lowest concentrated metabolites are still detected, even if their concentration is 1 million times weaker than that of the highest concentrated metabolites. 

In the second step, the spectrum measured in step one (=the sum of all signals from all metabolites) is resolved using proprietary AI algorithms. All metabolites present are identified and quantified by the software. Currently, lifespin can detect and quantify more than 1000 different metabolites.